Superoxide dismutases in parasitoids' venom

نویسندگان

  • Dominique Colinet
  • Dominique Cazes
  • Maya Belghazi
  • Jean-Luc Gatti
  • Marylène Poirié
چکیده

Background: Endoparasitoid wasps inject venom proteins at oviposition to alter host immunity. Results: The venom of Leptopilina boulardi but not of a related species contains an active extracellular SOD. Recombinant SODs inhibit the Drosophila host phenoloxidase activity. Conclusion: An extracellular SOD is secreted and active in an insect fluid. Significance: SODs may be used as immune suppressive virulence factors by parasitoid wasps.

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تاریخ انتشار 2011